Hormone therapy, is used either alone or in combination with surgery or radiation. It is based on the fact that prostate cancer cells frequently use the male hormone , testosterone as a fertilizer and the absence of this hormone may lead to the death or weakening of prostate cancer cells. So It is used to stop the production of testosterone hormone and hence a person with Stage C and D cancer can have their life extended and improved by the use of hormonal therapy.

There are side effects associated with Hormone therapy. They include hot flashes, weight gain, erectile dysfunction, decrease in muscle mass and strength, personality changes, decreased mentation and osteoporosis.