Musicplace.co.nr
If site is put on the right category, the content is attractive, and you can generate a few thumbs-ups, then you could potentially get to the high 100's within the first 48 hours. This is my experience with a relevant site, the first time I stumbled it (one stumble = answer to your question). I did wait until I had a pretty attractive piece of content before I did this. In my case, my site was a .org where I have a public domain ecology type project, it has no advertisement. But, commercial sites are encouraged by stumbleupon as long as their content is the right kind of content for the category.